Presence of the Tet M determinant in a clinical isolate of Acinetobacter baumannii.
نویسندگان
چکیده
The tet(M) gene encodes a protein which is related to tetracycline ribosomal protection, one of the mechanisms of tetracycline resistance. A tet(M) gene that is 100% homologous to the tet(M) gene of Staphylococcus aureus has been found in a clinical isolate of Acinetobacter baumannii, which also carries the tet(A) gene encoding a tetracycline efflux pump.
منابع مشابه
Partial characterization of a transposon containing the tet(A) determinant in a clinical isolate of Acinetobacter baumannii.
A genomic library from one clinical isolate of Acinetobacter baumannii was obtained to find genes responsible for tetracycline resistance. Escherichia coli DH5alpha-MDR transformants, selected on Mueller-Hinton agar supplemented with tetracycline 18 mg/L, were thoroughly characterized. In one clone, with an insert of 7,070 bp, it was found that the resistance to tetracycline was mediated by the...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 47 7 شماره
صفحات -
تاریخ انتشار 2003